Micronutrients and Diabetes

Patented technology to help to optimize cellular sugar metabolism Natural health research – the basis of preventive health

Patented technology to help to normalize high blood sugar levels – naturally

More than 60 million people in Europe suffer from diabetes, and hundreds of thousands die each year from complications of this disease. Diabetic disorders have a genetic background and are divided into two types: juvenile diabetes (Type 1), and adultonset diabetes (Type 2). Juvenile diabetes requires regular insulin injections from a young age. The majority of diabetic patients, however, develop this disease later in life. Until recently, the causes that trigger the sudden onset of the disease have been largely unknown, and treatment has consisted of lowering blood sugar levels with various drugs. However, diabetic cardiovascular complications occur even in those patients with controlled blood sugar levels. Thus, lowering blood sugar levels is a necessary but incomplete measure to address diabetic disorders.

New research shows that the primary cause of adult diabetes is a longterm deficiency of dietary vitamins and other essential nutrients in the cells of our body. This affects particularly the pancreas, the organ that produces insulin, and the blood vessel walls. Optimum intake of micronutrients can help to prevent the onset of adult diabetes and its complications.

Groundbreaking natural health research

Scientists at the Dr. Rath Research Institute have developed a combination of micronutrients that has been proven to affect decisive cellular mechanisms involved in diabetes.

  • Micronutrients increase glucose uptake by cells

One of the important ways to normalize elevated blood glucose levels is to optimize uptake of glucose by the cells of our body. The adjacent graph (A) shows that a combination of three micronutrient compositions (core, mineral and D3/K2), taken together, could enhance cellular glucose uptake more than fivefold compared to a control. Better cellular glucose uptake means less glucose in blood.

  • Micronutrients increase insulin secretion by pancreatic cells

Insufficient insulin production by the hormonal cells of the pancreas is a primary cause of diabetes. The results on the adjacent graph (B) show that specific micronutrient combinations can increase the secretion of insulin by pancreas cells in a natural way. At the highest micronutrient concentration tested in this study, the insulin secretion was twice as high as in controls. More insulin means more cellular glucose uptake and, hence, a lowering of high blood sugar.

  • Micronutrients help to protect nerve cells from diabetic damage

One of the longterm complications of diabetes is the deposition of dangerous byproducts generated by high glucose. These socalled Advanced Glycation End Products AGEs*) include certain proteins, lipids and other compounds. By becoming encrusted with sugar molecules, these AGEs can have a toxic effect on all cells, and in particular on the cells of the nervous system. Further results show that a triple combination of micronutrients can protect up to 80% of nerve (glial) cells from the deadly damages caused by AGEs. The more cells surviving high glucose damage, the better the nervous system is protected in diabetes.

Vitamin C
Vitamin B1
Vitamin B2
Vitamin B3
Vitamin B5
Vitamin B6
Vitamin B12
Vitamin E
Cinnamon Extract
Green Tea Extract
Alpha-Lipoic Acid
Grape Seed Extract

Micronutrient combinations help normalize high blood sugar levels

The following experiments were part of the scientific proof that led to the Patent Office approval of this natural technology to help fight diabetes.

Figure A shows that different micronutrient combinations (blue) can greatly increase the uptake of sugar by body cells, and thereby help to lower elevated blood sugar levels. Taken together, these micronutrient combinations can increase the sugar uptake more than fivefold compared to controls.

Figure B documents another breakthrough experiment from this patent. Micronutrient combinations can stimulate the production/secretion of insulin — the decisive sugarlevelregulating hormone – in human pancreas cells. Thus, optimum micronutrient supplementation contributes to optimum availability of insulin in healthy people and to insulinsparing in diabetic patients.

A. Micronutrient combinations increase cellular sugar uptake as a precondition for normalizing high blood sugar

B. Micronutrient combinations increase insulin secretion of human pancreas cells

Nobel Prize‐winner‐supported research paves the way to preventive health care

The Dr. Rath Research Institute is a world leader in sciencebased natural health. Three decades ago, Dr. Matthias Rath – together with twotime Nobel Laureate Dr. Linus Pauling (†1994) – was already publishing groundbreaking discoveries on the importance of vitamins in fighting cardiovascular diseases. Over the ensuing decades, the Institute’s research team, under the leadership of Dr. Aleksandra Niedzwiecki, has extended this lifesaving research to comprise natural prevention of cancer, diabetes, viral and bacterial infections and many other diseases. The approval of this preventive health research by patent offices around the world provides the scientific basis for effective preventive health strategies globally. Patients, therapists, governments and, above all, millions of people now have effective, safe, natural health approaches avilable to help to prevent widespread diseases.

The Dr. Rath organization operates under a nonprofit roof and all profits are used to promote further independent research and education in natural health. This information sheet provides health research established in connection with natural disease prevention. For patients, we recommend to see a therapist or trained consultant to determine your individual health needs.

‘Science‐based natural health is the basis of modern, preventive health care. The time to build it is now!’

Dr. Matthias Rath

What this patent means

This specific health technology is

  • recognized by a government agency,
  • novel and has not existed before,
  • unique and not available anywhere else,
  • protected and cannot be imitated.

What is the difference from a pharmaceutical drug patent?

Farmaceutische investeringsbranche Natuurgeneeskundige gemeenschap
Marktdoelen Zaken doen in ziekte Preventie van ziekte
Doel van patenten Wettelijke middelen om investeringsrendement zeker te stellen Wetenschappelijke erkenning
Gevolgen voor uw gezondheid Bevestiging van het voortbestaan van ziekten als wereldmarkt Preventie en mogelijk uitroeien van ziekten

Supporting Studies

Type 1

Combinatie van B-vitamines bij beginnende diabetische nefropathie in kinderen met type 1 diabetes

Het effect van vitamine D supplementatie bij kinderen met type 1 diabetes

Het effect van vitamine D op glucosewaarden in kinderen en jongeren met diabetes type 1

Chroom, zink en magnesium bij type 1 diabetes

Immunologisch effect van vitamine D en de rol bij de preventie en behandeling van type 1 diabetes

De rol van vitamine D supplementatie bij patiënten met diabetes type 1


Type 2

Het effect van orale vitamine D supplementatie op glucose regulatie in patiënten met type 2 diabetes

Het effect van vitamine C en E supplementatie bij type 2 Diabetes

Het effect van gecombineerde magnesium en zink supplementatie op het metabolisme van patiënten met type 2 diabetes en hart- en vaatziekten

Vitamine C supplementatie verbetert regulatie van glucosewaarden en bloeddrukwaarden bij type 2 diabetes

Vitamine D supplementatie in relatie tot (pre)diabetes type 2

Het effect van vitamine D supplementatie op glucosewaarden en de voortgang van prediabetes naar diabetes

De positieve rol van micronutriënten supplementatie op neuropathie bij type 2 diabetes

De effecten van zink en andere micronutriënten op het glucose- en vetmetabolisme bij volwassen diabetici

Het effect van foliumzuur supplementatie op diverse metabolische factoren bij mannen met overgewicht en obesitas met type 2 diabetes

Het effect van magnesium supplementatie op de glucosestofwisseling in mensen met diabetes of met een verhoogd risico op diabetes

Gestational Diabetes

Het effect van vitamine D supplementatie bij zwangere vrouwen met zwangerschapsdiabetes

Het effect van zink supplementatie op het metabolisme bij zwangerschapsdiabetes

De effecten van selenium supplementatie op de glucoseregulatie, ontstekingsfactoren, en oxidatieve stress levels bij zwangerschapsdiabetes

De effecten van magnesium en vitamine E supplementatie op glucoseregulatie en vetstofwisseling in patiënten met zwangerschapsdiabetes

De rol van vitamine D en calcium supplementatie op het metabolisme en oxidatieve stress bij zwangerschapsdiabetes

Supplementatie met een combinatie van magnesium, zink, calcium en vitamine D verbetert glucosewaarden en risicofactoren voor hart- en vaatziekten bij zwangerschapsdiabetes